Article
Targeting Macrophage Phenotypes and Metabolism as Novel Therapeutic Approaches in Atherosclerosis and Related Cardiovascular Diseases.
Current atherosclerosis reports - 1 Oct 2024
Wang Juan, Wu Qiang, Wang Xinyu, Liu Hongbin, Chen Mulei, Xu Li, Zhang Ze, Li Kuibao, Li Weiming, Zhong Jiuchang
Abstract excerpt
PURPOSE OF THE REVIEW: Macrophage accumulation and activation function as hallmarks of atherosclerosis and have complex and intricate dynamics throughout all components and stages of atherosclerotic plaques. In this review, we focus on the regulatory roles and underlying mechanisms of macrophage phenotypes and metabolism in atherosclerosis. We highlight the diverse range of macrophage phenotypes present in...
Topics
- Humans
- Atherosclerosis
- Macrophages
- Phenotype
- Animals
- Plaque, Atherosclerotic
- Macrophage Activation
- Cardiovascular Diseases