Article
Functional diversity of macrophages in vascular biology and disease.
Vascular pharmacology - 1 Dec 2017
Park Inhye, Kassiteridi Christina, Monaco Claudia
Abstract excerpt
Atherosclerosis is a multifactorial chronic inflammatory disease and is largely responsible for cardiovascular disease, the most common cause of global mortality. The hallmark of atherogenesis is immune activation following lipid accumulation in the arterial wall. In particular, macrophages play a non-redundant role in both the progression and regression of inflammation in the atherosclerotic lesion. Macrophages...
Topics
- Animals
- Anti-Inflammatory Agents
- Arteries
- Atherosclerosis
- Cellular Microenvironment
- Humans
- Inflammation
- Inflammation Mediators
- Macrophages
- Phenotype
- Transcription Factors