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Article

Modeling miRNA-mRNA interactions that cause phenotypic abnormality in breast cancer patients.

PloS one - 1 Jan 2017

Lee Sanghoon, Jiang Xia

Abstract excerpt

BACKGROUND: The dysregulation of microRNAs (miRNAs) alters expression level of pro-oncogenic or tumor suppressive mRNAs in breast cancer, and in the long run, causes multiple biological abnormalities. Identification of such interactions of miRNA-mRNA requires integrative analysis of miRNA-mRNA expression profile data. However, current approaches have limitations to consider the regulatory relationship between...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28793339
DOI: 10.1371/journal.pone.0182666
PMCID: PMC5549916

Genes

CCND2
ESR1
MET
NOTCH1
TGFB1
TGFBR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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