Article
Integrated miRNA and mRNA expression profiling of the inflammatory breast cancer subtype.
British journal of cancer - 10 Aug 2010
Van der Auwera I, Limame R, van Dam P, Vermeulen P B, Dirix L Y, Van Laere S J
Abstract excerpt
BACKGROUND: MicroRNAs (miRNAs) are key regulators of gene expression. In this study, we explored whether altered miRNA expression has a prominent role in defining the inflammatory breast cancer (IBC) phenotype. METHODS: We used quantitative PCR technology to evaluate the expression of 384 miRNAs in 20 IBC and 50 non-IBC samples. To gain understanding on the biological functions deregulated by aberrant miRNA...
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