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Article

Deciphering causal and statistical relations of molecular aberrations and gene expressions in NCI-60 cell lines.

BMC systems biology - 4 Nov 2011

Li Shyh-Dar, Tagami Tatsuaki, Ho Ying-Fu, Yeang Chen-Hsiang

Abstract excerpt

BACKGROUND: Cancer cells harbor a large number of molecular alterations such as mutations, amplifications and deletions on DNA sequences and epigenetic changes on DNA methylations. These aberrations may dysregulate gene expressions, which in turn drive the malignancy of tumors. Deciphering the causal and statistical relations of molecular aberrations and gene expressions is critical for understanding the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 22051105
DOI: 10.1186/1752-0509-5-186
PMCID: PMC3259106

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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