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Article

Functional genomic exploration reveals that Ss-RIOK-1 is essential for the development and survival of Strongyloides stercoralis larvae.

International journal for parasitology - 1 Dec 2017

Yuan Wang, Zhou Huan, Lok James B, Lei Weiqiang, He Siyuan, Gasser Robin B, Zhou Rui, Fang Rui, Zhou Yanqin, Zhao Junlong, Hu Min

Abstract excerpt

Protein kinase RIOK-1 is a non-ribosomal factor essential for rRNA cleavage and ribosome small subunit maturation. It is encoded in all eukaryotic organisms. The RIOK-1 encoding gene of Caenorhabditis elegans (Ce-riok-1) is expressed in the neuronal and reproductive systems in larvae and adults of this free-living nematode, and it supports larval growth and development of the adult gonad. In spite of its...

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Identifiers

PMID: 28780152
DOI: 10.1016/j.ijpara.2017.06.005
PMCID: PMC6381600

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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