Article
MAIT Cells Are Enriched and Highly Functional in Ascites of Patients With Decompensated Liver Cirrhosis.
Hepatology (Baltimore, Md.) - 1 Oct 2020
Niehaus Christian E, Strunz Benedikt, Cornillet Martin, Falk Christine S, Schnieders Ansgar, Maasoumy Benjamin, Hardtke Svenja, Manns Michael P, Kraft Anke R M, Björkström Niklas K, Cornberg Markus
Abstract excerpt
BACKGROUND AND AIMS: Patients with advanced liver cirrhosis have an increased susceptibility to infections. As part of the cirrhosis-associated immune dysfunction, mucosal-associated invariant T (MAIT) cells, which have the capacity to respond to bacteria, are severely diminished in circulation and liver tissue. However, MAIT cell presence and function in the peritoneal cavity, a common anatomical site for...
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