Article
Anomalous baroreflex functionality inherent in floxed and Cre-Lox mice: an overlooked physiological phenotype.
American journal of physiology. Heart and circulatory physiology - 1 Oct 2017
Tsai Ching-Yi, Poon Yan-Yuen, Chen Chang-Han, Chan Samuel H H
Abstract excerpt
The last two decades have seen the emergence of Cre-Lox recombination as one of the most powerful and versatile technologies for cell-specific genetic engineering of mammalian cells. Understandably, the primary concerns in the practice of Cre-Lox recombination are whether the predicted genome has been correctly modified and the targeted phenotypes expressed. Rarely are the physiological conditions of the animals...
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