Genome-wide association studies and the clinic: a focus on breast cancer.

Abstract excerpt

Breast cancer is the most frequently diagnosed cancer among women worldwide, and has long been considered to be a genetic disease. A wide range of genetic variants, both rare mutations and more common variants, have been shown to influence breast cancer risk. In particular, recent studies have identified a number of common genetic variants, or single nucleotide polymorphisms, that are associated with breast...

Topics

• Biomarkers, Tumor
• Breast Neoplasms
• Female
• Genetic Predisposition to Disease
• Genome-Wide Association Study
• Humans
• Polymorphism, Single Nucleotide
• Risk Factors