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Article

Sexual dimorphism in glioma glycolysis underlies sex differences in survival

2 Aug 2017

Abstract excerpt

The molecular bases for sex differences in cancer remain undefined and how to incorporate them into risk stratification remains undetermined. Given sex differences in metabolism and the inverse correlation between fluorodeoxyglucose (FDG) uptake and survival, we hypothesized that glycolytic phenotyping would improve glioma subtyping. Using retrospectively acquired lower-grade glioma (LGG) transcriptome data from...

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PMID: 28768910
DOI: 10.1172/jci.insight.92142

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