Article
Anti-inflammatory effects of exercise training in adipose tissue do not require FGF21.
The Journal of endocrinology - 1 Nov 2017
Porter Jay W, Rowles Joe L, Fletcher Justin A, Zidon Terese M, Winn Nathan C, McCabe Leighton T, Park Young-Min, Perfield James W, Thyfault John P, Rector R Scott, Padilla Jaume, Vieira-Potter Victoria J
Abstract excerpt
Exercise enhances insulin sensitivity; it also improves adipocyte metabolism and reduces adipose tissue inflammation through poorly defined mechanisms. Fibroblast growth factor 21 (FGF21) is a pleiotropic hormone-like protein whose insulin-sensitizing properties are predominantly mediated via receptor signaling in adipose tissue (AT). Recently, FGF21 has also been demonstrated to have anti-inflammatory...
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