Article
The contribution of p53 and Y chromosome long arm genes to regulation of apoptosis in mouse testis.
Reproduction, fertility, and development - 1 Mar 2018
Lech Tomasz, Styrna Józefa, Kotarska Katarzyna
Abstract excerpt
Apoptosis of excessive or defective germ cells is a natural process occurring in mammalian testes. Tumour suppressor protein p53 is involved in this process both in developing and adult male gonads. Its contribution to testicular physiology is known to be modified by genetic background. The aim of this study was to evaluate the combined influence of the p53 and Y chromosome long arm genes on male germ cell...
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