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Regulation of Oocyte Apoptosis: A View from Gene Knockout Mice

10 Jan 2023

Abstract excerpt

Apoptosis is a form of programmed cell death that plays a critical role in cellular homeostasis and development, including in the ovarian reserve. In humans, hundreds of thousands of oocytes are produced in the fetal ovary. However, the majority die by apoptosis before birth. After puberty, primordial follicles develop into mature follicles. While only a large dominant follicle is selected to ovulate, smaller...

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PMID: 36674865
DOI: 10.3390/ijms24021345

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