Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Experimental Cryptorchidism Induces Testicular Germ Cell Apoptosis by p53-Dependent and -Independent Pathways In Mice

1 Feb 1998

Abstract excerpt

Cryptorchidism is associated with male infertility: germ cell loss occurs by apoptosis in response to elevated temperature. Since the tumor suppressor p53 is highly expressed in the testis and is known to induce apoptosis, an investigation was undertaken to establish whether heat stress causes p53-mediated germ cell apoptosis. Using a mouse model of experimental unilateral cryptorchidism, it was observed that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell death mechanisms and regulation
Share to Sperm and Testicular Function
Share to Testicular diseases and treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9475406
DOI: 10.1095/biolreprod58.2.492

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Experimental Cryptorchidism Induces Testicular Germ Cell Apoptosis by p53-Dependent and -Independent Pathways In MicePMID 9475406Read ↗

p53 and Fas Are Sequential Mechanisms of Testicular Germ Cell ApoptosisSemantic proximity Read ↗

Functional analysis of the p53 gene in apoptosis induced by heat stress or loss of stem cell factor signaling in mouse male germ cells.Semantic proximity Read ↗

Experimentally Induced Cryptorchidism Increases Apoptosis in Rat Testis1Semantic proximity Read ↗

Male germ cell apoptosis: regulation and biologySemantic proximity Read ↗

Apoptosis and expression of apoptosis-related genes in the mouse testis following heat exposureSemantic proximity Read ↗

Whole‐body heat exposure causes developmental stage‐specific apoptosis of male germ cellsSemantic proximity Read ↗

Expression of a K48R mutant ubiquitin protects mouse testis from cryptorchid injury and aging.Semantic proximity Read ↗

Xanthine oxidase inhibitors suppress testicular germ cell apoptosis induced by experimental cryptorchidismSemantic proximity Read ↗

Role of Caspase 2 in Apoptotic Signaling in Primate and Murine Germ Cells1Semantic proximity Read ↗

Functional role of inducible nitric oxide synthase in the induction of male germ cell apoptosis, regulation of sperm number, and determination of testes size: evidence from null mutant mice.Semantic proximity Read ↗

Hormonal and genetic control of germ cell apoptosis in the testisSemantic proximity Read ↗

Hormonal and genetic control of germ cell apoptosis in the testisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.