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Article

Individual differences in circadian locomotor parameters correlate with anxiety- and depression-like behavior.

PloS one - 1 Jan 2017

Anyan Jeffrey, Verwey Michael, Amir Shimon

Abstract excerpt

Disrupted circadian rhythms are a core feature of mood and anxiety disorders. Circadian rhythms are coordinated by a light-entrainable master clock located in the suprachiasmatic nucleus. Animal models of mood and anxiety disorders often exhibit blunted rhythms in locomotor activity and clock gene expression. Interestingly, the changes in circadian rhythms correlate with mood-related behaviours. Although animal...

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Identifiers

PMID: 28763478
DOI: 10.1371/journal.pone.0181375
PMCID: PMC5538649

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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