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Article

Conditioned Medium from Malignant Breast Cancer Cells Induces an EMT-Like Phenotype and an Altered N-Glycan Profile in Normal Epithelial MCF10A Cells.

International journal of molecular sciences - 1 Aug 2017

Guo Jia, Liu Changmei, Zhou Xiaoman, Xu Xiaoqiang, Deng Linhong, Li Xiang, Guan Feng

Abstract excerpt

Epithelial-mesenchymal transition (EMT) is a key process in cancer development and progression. Communication (crosstalk) between cancer cells and normal (nonmalignant) cells may facilitate cancer progression. Conditioned medium (CM) obtained from cultured cancer cells contains secreted factors capable of affecting phenotypes and the behaviors of normal cells. In this study, a culture of normal breast epithelial...

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Identifiers

PMID: 28763000
DOI: 10.3390/ijms18081528
PMCID: PMC5577993

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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