Article
Gene expression of the invasive phenotype of TNF-alpha-treated MCF-7 cells.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Jul 2009
Yin Yongmei, Chen Xiaofeng, Shu Yongqian
Abstract excerpt
BACKGROUND AND OBJECTIVES: TNF-alpha secreted by tumor cells and macrophages that have infiltrated into the micro-environment of a tumor may promote the metastasis of a variety of malignant cancers, including breast cancer. The present study was designed to detect gene expression changes in metastatic MCF-7 cells treated with a low dose of TNF-alpha (20ng/mL), and to further explore the mechanisms by which...
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