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Article

Structure and Function of Human Tyrosinase and Tyrosinase-Related Proteins.

Chemistry (Weinheim an der Bergstrasse, Germany) - 2 Jan 2018

Lai Xuelei, Wichers Harry J, Soler-Lopez Montserrat, Dijkstra Bauke W

Abstract excerpt

Melanin is the main pigment responsible for the color of human skin, hair and eye. Its biosynthesis requires three melanogenic enzymes, tyrosinase (TYR), and the tyrosinase-related proteins TYRP1 and TYRP2. The difficulty of isolating pure and homogeneous proteins from endogenous sources has hampered their study, and resulted in many contradictory findings regarding their physiological functions. In this review,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29052256
DOI: 10.1002/chem.201704410

Genes

TYR
TYRP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Structure and Function of Human Tyrosinase and Tyrosinase-Related Proteins.PMID 29052256Read ↗

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