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Article

Structural Basis for Substrate Recognition by the Ankyrin Repeat Domain of Human DHHC17 Palmitoyltransferase.

Structure (London, England : 1993) - 5 Sept 2017

Verardi Raffaello, Kim Jin-Sik, Ghirlando Rodolfo, Banerjee Anirban

Abstract excerpt

DHHC enzymes catalyze palmitoylation, a major post-translational modification that regulates a number of key cellular processes. There are up to 24 DHHCs in mammals and hundreds of substrate proteins that get palmitoylated. However, how DHHC enzymes engage with their substrates is still poorly understood. There is currently no structural information about the interaction between any DHHC enzyme and protein...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28757145
DOI: 10.1016/j.str.2017.06.018
PMCID: PMC5599134

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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