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Article

Functional analysis of human aromatic amino acid transporter MCT10/TAT1 using the yeast Saccharomyces cerevisiae.

Biochimica et biophysica acta. Biomembranes - 1 Oct 2017

Uemura Satoshi, Mochizuki Takahiro, Kurosaka Goyu, Hashimoto Takanori, Masukawa Yuki, Abe Fumiyoshi

Abstract excerpt

Tryptophan is an essential amino acid in humans and an important serotonin and melatonin precursor. Monocarboxylate transporter MCT10 is a member of the SLC16A family proteins that mediates low-affinity tryptophan transport across basolateral membranes of kidney, small intestine, and liver epithelial cells, although the precise transport mechanism remains unclear. Here we developed a simple functional assay to...

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PMID: 28754537
DOI: 10.1016/j.bbamem.2017.07.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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