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Article

Ankyrin-1 Gene Exhibits Allelic Heterogeneity in Conferring Protection Against Malaria.

G3 (Bethesda, Md.) - 7 Sept 2017

Huang Hong Ming, Bauer Denis C, Lelliott Patrick M, Dixon Matthew W A, Tilley Leann, McMorran Brendan J, Foote Simon J, Burgio Gaetan

Abstract excerpt

Allelic heterogeneity is a common phenomenon where a gene exhibits a different phenotype depending on the nature of its genetic mutations. In the context of genes affecting malaria susceptibility, it allowed us to explore and understand the intricate host-parasite interactions during malaria infections. In this study, we described a gene encoding erythrocytic ankyrin-1 (Ank-1) which exhibits allelic-dependent...

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Identifiers

PMID: 28751503
DOI: 10.1534/g3.117.300079
PMCID: PMC5592938

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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