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Article

Virulence of an H5N8 highly pathogenic avian influenza is enhanced by the amino acid substitutions PB2 E627K and HA A149V

25 Jul 2017

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 28750900
DOI: 10.1016/j.meegid.2017.07.026

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Related research

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Click a neighbor to travelStep 1 · 12 closest

Virulence of an H5N8 highly pathogenic avian influenza is enhanced by the amino acid substitutions PB2 E627K and HA A149VPMID 28750900Read ↗

PB2 substitutions V598T/I increase the virulence of H7N9 influenza A virus in mammalsSemantic proximity Read ↗

Novel residues in avian influenza virus PB2 protein affect virulence in mammalian hosts.Semantic proximity Read ↗

PB2-E627K and PA-T97I substitutions enhance polymerase activity and confer a virulent phenotype to an H6N1 avian influenza virus in miceSemantic proximity Read ↗

PB2-Q591K Mutation Determines the Pathogenicity of Avian H9N2 Influenza Viruses for Mammalian SpeciesSemantic proximity Read ↗

Synergistic effect of PB2 283M and 526R contributes to enhanced virulence of H5N8 influenza viruses in miceSemantic proximity Read ↗

Substitutions in the PB2 methionine 283 residue affect H5 subtype avian influenza virus virulence.Semantic proximity Read ↗

Amino acid mutations PB1-V719M and PA-N444D combined with PB2-627K contribute to the pathogenicity of H7N9 in mice.Semantic proximity Read ↗

H5N1 Influenza Virulence, Pathogenicity and Transmissibility: What do We Know?Semantic proximity Read ↗

Altered virulence of Highly Pathogenic Avian Influenza (HPAI) H5N8 reassortant viruses in mammalian modelsSemantic proximity Read ↗

Prerequisites for the acquisition of mammalian pathogenicity by influenza A virus with a prototypic avian PB2 gene.Semantic proximity Read ↗

The PB2-K627E mutation attenuates H3N2 swine influenza virus in cultured cells and in mice.Semantic proximity Read ↗

The PB2 mutation with lysine at 627 enhances the pathogenicity of avian influenza (H7N9) virus which belongs to a non-zoonotic lineageSemantic proximity Read ↗

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