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Article

A novel method for monitoring glucocorticoid-induced changes of the glucocorticoid receptor in kidney transplant recipients.

Transplant immunology - 1 Mar 2009

Chen Yan, Burckart Gilbert J, Shah Tariq, Pravica Vera, Hutchinson Ian V

Abstract excerpt

INTRODUCTION: Initial high dose glucocorticosteroid (GC) treatment of transplant recipients induces changes in the glucocorticoid receptor (GR) that may affect the mode of action of the drug. We developed a TaqMan one-step RT-PCR quantification method to investigate the effect of bolus GC treatment on the structure of the GR complex by measuring the levels of GR isoform expression and FK binding protein 5 (FKBP5)...

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Source

Identifiers

PMID: 19162184
DOI: 10.1016/j.trim.2008.12.003

Genes

FKBP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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