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Article

Evaluation of exome variants using the Ion Proton Platform to sequence error-prone regions.

PloS one - 1 Jan 2017

Seo Heewon, Park Yoomi, Min Byung Joo, Seo Myung Eui, Kim Ju Han

Abstract excerpt

The Ion Proton sequencer from Thermo Fisher accurately determines sequence variants from target regions with a rapid turnaround time at a low cost. However, misleading variant-calling errors can occur. We performed a systematic evaluation and manual curation of read-level alignments for the 675 ultrarare variants reported by the Ion Proton sequencer from 27 whole-exome sequencing data but that are not present in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28742110
DOI: 10.1371/journal.pone.0181304
PMCID: PMC5524428

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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