Article
Association of BRCA2 Gene Functional Polymorphisms with Nonsyndromic Cleft Lip With or Without Cleft Palate in a Chinese Population.
Genetic testing and molecular biomarkers - 1 May 2023
Guo Siyuan, Zhou Zuo, Guo Tingting, Xu Yi, Yang Xintao, Wang Yupei, Chen Renji
Abstract excerpt
Background: Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is a complex congenital disease affected by genetic and environmental factors however, the specific pathogenic alleles and regulatory mechanisms remain unclear in many cases. Here, we aimed to study the association between eight potentially functional single nucleotide polymorphisms (SNPs) of the BRCA2 and MGMT genes and NSCL/P in a Chinese...
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