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Article

Trajectories of depressive and anxiety symptoms in older adults: a 6-year prospective cohort study.

International journal of geriatric psychiatry - 1 Feb 2018

Holmes Sophie E, Esterlis Irina, Mazure Carolyn M, Lim Yen Ying, Ames David, Rainey-Smith Stephanie, Fowler Chris, Ellis Kathryn, Martins Ralph N, Salvado Olivier, Doré Vincent, Villemagne Victor L, Rowe Christopher C, Laws Simon M, Masters Colin L, Pietrzak Robert H, Maruff Paul

Abstract excerpt

OBJECTIVE: Depressive and anxiety symptoms are common in older adults, significantly affect quality of life, and are risk factors for Alzheimer's disease. We sought to identify the determinants of predominant trajectories of depressive and anxiety symptoms in cognitively normal older adults. METHOD: Four hundred twenty-three older adults recruited from the general community underwent Aβ positron emission...

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PMID: 28736899
DOI: 10.1002/gps.4761
PMCID: PMC5773367

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