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Article

Effects of Different Centrifugation Protocols on the Detection of EGFR Mutations in Plasma Cell-Free DNA.

American journal of clinical pathology - 4 Aug 2022

Shin Kyung-Hwa, Lee Sun Min, Park Kongkyoung, Choi Hyunji, Kim In-Suk, Yoon Seong Hoon, Oh Seung Hwan

Abstract excerpt

OBJECTIVES: Various preanalytical factors, including the collection tube, storage conditions, and centrifugation, affect the detection results of plasma cell-free DNA (cfDNA). We compared the effect of different centrifugation protocols on the detection of EGFR mutations in cfDNA. METHODS: We analyzed 117 plasma specimens from 110 patients with non-small cell lung cancer using the cobas EGFR Mutation Test v2...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35285877
DOI: 10.1093/ajcp/aqac024
PMCID: PMC9350828

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