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Article

IFNL4 rs368234815 and rs117648444 variants predict off-treatment HBsAg seroclearance in IFN-treated HBeAg-negative chronic hepatitis B patients.

Liver international : official journal of the International Association for the Study of the Liver - 1 Mar 2018

Galmozzi Enrico, Facchetti Floriana, Grossi Glenda, Loglio Alessandro, Viganò Mauro, Lunghi Giovanna, Colombo Massimo, Lampertico Pietro

Abstract excerpt

BACKGROUND & AIM: Robust baseline predictors of interferon (IFN) response in HBeAg-negative chronic hepatitis B (CHB) patients are not currently available. The recently described rs368234815 TT/ΔG dinucleotide and rs117648444 nonsynonymous P70S polymorphisms in IFN lambda 4 (IFNL4) gene, which are strongly associated with response to IFN in hepatitis C virus (HCV) infection, could be also useful in IFN-treated...

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PMID: 28732143
DOI: 10.1111/liv.13526

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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