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Article

IFNL4 polymorphism predicts response to hepatitis C treatment after liver transplantation.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Oct 2014

Fernández-Carrillo Carlos, Coto-Llerena Mairene, González Patricia, Crespo Gonzalo, Mensa Laura, Caro-Pérez Noelia, Gambato Martina, Navasa Miquel, Forns Xavier, Pérez-del-Pulgar Sofía

Abstract excerpt

BACKGROUND: Recent studies in chronic hepatitis C patients have shown that rs368234815 polymorphism nearby IL28B is a better predictor of response to antiviral treatment with pegylated interferon and ribavirin than IL28B polymorphisms (rs12979860 and rs8099917). Its effect could be related to interferon lambda 4 (IFNL4), a protein which seems to confer some paradoxical disadvantages in hepatitis C virus (HCV)...

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Identifiers

PMID: 25130512
DOI: 10.1016/j.jcv.2014.07.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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