Article
Genomic abnormalities in invasive endocervical adenocarcinoma correlate with pattern of invasion: biologic and clinical implications.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Nov 2017
Hodgson Anjelica, Amemiya Yutaka, Seth Arun, Cesari Matthew, Djordjevic Bojana, Parra-Herran Carlos
Abstract excerpt
The pattern-based classification system for HPV-related endocervical adenocarcinoma, which classifies tumors based on the destructiveness of stromal invasion, is predictive of the risk of nodal metastases and adverse outcome. Previous studies have demonstrated clinically important molecular alterations in endocervical adenocarcinoma, including KRAS and PIK3CA mutations; however, correlation between the molecular...
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