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Article

Cotranscriptional Production of Chemically Modified RNA Nanoparticles.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017

Kireeva Maria L, Afonin Kirill A, Shapiro Bruce A, Kashlev Mikhail

Abstract excerpt

RNA nanoparticles consisting of multiple RNA strands of different sequences forming various three-dimensional structures emerge as promising carriers of siRNAs, RNA aptamers, and ribozymes. In vitro transcription of a mixture of dsDNA templates encoding all the subunits of the RNA nanoparticle may result in cotranscriptional self-assembly of the nanoparticle. Based on our experience with production of RNA...

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Identifiers

PMID: 28730434
DOI: 10.1007/978-1-4939-7138-1_6
PMCID: PMC7927353

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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