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Article

ErbB4 deletion accelerates renal fibrosis following renal injury.

American journal of physiology. Renal physiology - 1 May 2018

Zeng Fenghua, Miyazawa Tomoki, Kloepfer Lance A, Harris Raymond C

Abstract excerpt

Tubulointerstitial fibrosis (TIF) is a prominent factor in the progression of chronic kidney disease regardless of etiology. Avian erythroblastic leukemia viral oncogene homolog 4 (ErbB4) expression levels were inversely correlated to renal fibrosis in human fibrotic kidneys. In both unilateral ureteral obstruction (UUO) and ischemia-reperfusion injury followed by uninephrectomy (IRI/UNx) mouse models, expression...

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Identifiers

PMID: 28724608
DOI: 10.1152/ajprenal.00260.2017
PMCID: PMC6031915

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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