Article
Genome analysis of E. coli isolated from Crohn's disease patients.
BMC genomics - 19 Jul 2017
Rakitina Daria V, Manolov Alexander I, Kanygina Alexandra V, Garushyants Sofya K, Baikova Julia P, Alexeev Dmitry G, Ladygina Valentina G, Kostryukova Elena S, Larin Andrei K, Semashko Tatiana A, Karpova Irina Y, Babenko Vladislav V, Ismagilova Ruzilya K, Malanin Sergei Y, Gelfand Mikhail S, Ilina Elena N, Gorodnichev Roman B, Lisitsyna Eugenia S, Aleshkin Gennady I, Scherbakov Petr L, Khalif Igor L, Shapina Marina V, Maev Igor V, Andreev Dmitry N, Govorun Vadim M
Abstract excerpt
BACKGROUND: Escherichia coli (E. coli) has been increasingly implicated in the pathogenesis of Crohn's disease (CD). The phylogeny of E. coli isolated from Crohn's disease patients (CDEC) was controversial, and while genotyping results suggested heterogeneity, the sequenced strains of E. coli from CD patients were closely related. RESULTS: We performed the shotgun genome sequencing of 28 E. coli isolates from ten...
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