Article
Outer nuclear membrane protein Kuduk modulates the LINC complex and nuclear envelope architecture.
The Journal of cell biology - 4 Sept 2017
Ding Zhao-Ying, Wang Ying-Hsuan, Huang Yu-Cheng, Lee Myong-Chol, Tseng Min-Jen, Chi Ya-Hui, Huang Min-Lang
Abstract excerpt
Linker of nucleoskeleton and cytoskeleton (LINC) complexes spanning the nuclear envelope (NE) contribute to nucleocytoskeletal force transduction. A few NE proteins have been found to regulate the LINC complex. In this study, we identify one, Kuduk (Kud), which can reside at the outer nuclear membrane and is required for the development of Drosophila melanogaster ovarian follicles and NE morphology of myonuclei....
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