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Article

Association of EV71 3C polymorphisms with clinical severity.

Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi - 1 Oct 2018

Ma Hsuan-Yin, Lu Chun-Yi, Tsao Kuo-Chien, Shih Hsiu-Ming, Cheng Ai-Ling, Huang Li-Min, Chang Luan-Yin

Abstract excerpt

OBJECTIVES: Enterovirus 71 (EV71) may cause neurological and fatal cases. EV71 3C plays an important role on viral replication and possess proteolysis activity. To delineate pathogenesis of EV71 virulence, we studied EV71 3C genetics, protease activity and correlated the results with clinical severity. METHODS: EV71 cases were collected; 3C of EV71 was sequenced and linked with clinical severity. 3C protease...

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Identifiers

PMID: 28711442
DOI: 10.1016/j.jmii.2016.12.006

Genes

TRIM21

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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