Article
Sequence analysis-based characterization and identification of neurovirulence-associated variants of 36 EV71 strains from China.
Journal of medical virology - 1 Aug 2018
Xu Jun, Wang Fang, Zhao Desheng, Liu Jiang, Su Hong, Wang Baolong
Abstract excerpt
Enterovirus 71 (EV71) is the main pathogen of hand-foot-mouth disease (HFMD) and causes several neurological complications. As new strains of EV71 are constantly discovered, it is important to understand the genomic characteristics of the viruses and the mechanism of virulence. Herein, we isolated five strains of EV71 from HFMD patients with or without neurovirulence and sequenced their whole genomes. We then...
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