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Article

microRNA-206 modulates an Rtn4a/Cxcr4a/Thbs3a axis in newly forming somites to maintain and stabilize the somite boundary formation of zebrafish embryos.

Open biology - 1 Jul 2017

Lin Cheng-Yung, He Jun-Yu, Zeng Chih-Wei, Loo Moo-Rumg, Chang Wen-Yen, Zhang Po-Hsiang, Tsai Huai-Jen

Abstract excerpt

Although microRNA-206 (miR-206) is known to regulate proliferation and differentiation of muscle fibroblasts, the role of miR-206 in early-stage somite development is still unknown. During somitogenesis of zebrafish embryos, reticulon4a (rtn4a) is specifically repressed by miR-206. The somite boundary was defective, and actin filaments were crossing over the boundary in either miR-206-knockdown or...

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PMID: 28701377
DOI: 10.1098/rsob.170009
PMCID: PMC5541343

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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