Article
Full biological characterization of human pluripotent stem cells will open the door to translational research.
Archives of toxicology - 1 Sept 2016
Kramer Nina, Rosner Margit, Kovacic Boris, Hengstschläger Markus
Abstract excerpt
Since the discovery of human embryonic stem cells (hESC) and human-induced pluripotent stem cells (hiPSC), great hopes were held for their therapeutic application including disease modeling, drug discovery screenings, toxicological screenings and regenerative therapy. hESC and hiPSC have the advantage of indefinite self-renewal, thereby generating an inexhaustible pool of cells with, e.g., specific genotype for...
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