Article
Type I interferon-mediated monogenic autoinflammation: The type I interferonopathies, a conceptual overview.
The Journal of experimental medicine - 14 Nov 2016
Rodero Mathieu P, Crow Yanick J
Abstract excerpt
Type I interferon is a potent substance. As such, the induction, transmission, and resolution of the type I interferon-mediated immune response are tightly regulated. As defined, the type I interferonopathies represent discrete examples of a disturbance of the homeostatic control of this system caused by Mendelian mutations. Considering the complexity of the interferon response, the identification of further...
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