Article
Local Cues Establish and Maintain Region-Specific Phenotypes of Basal Ganglia Microglia.
Neuron - 19 Jul 2017
De Biase Lindsay M, Schuebel Kornel E, Fusfeld Zachary H, Jair Kamwing, Hawes Isobel A, Cimbro Raffaello, Zhang Hai-Ying, Liu Qing-Rong, Shen Hui, Xi Zheng-Xiong, Goldman David, Bonci Antonello
Abstract excerpt
Microglia play critical roles in tissue homeostasis and can also modulate neuronal function and synaptic connectivity. In contrast to astrocytes and oligodendrocytes, which arise from multiple progenitor pools, microglia arise from yolk sac progenitors and are widely considered to be equivalent throughout the CNS. However, little is known about basic properties of deep brain microglia, such as those within the...
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