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Article

Antigen-specific regulatory T cells: are police CARs the answer?

Translational research : the journal of laboratory and clinical medicine - 1 Sept 2017

Dawson Nicholas A J, Levings Megan K

Abstract excerpt

Cellular therapy with T-regulatory cells (Tregs) is a promising strategy to control immune responses and restore immune tolerance in a variety of immune-mediated diseases, such as transplant rejection and autoimmunity. Multiple clinical trials are currently testing this approach, typically by infusing a single dose of polyclonal Tregs that have been expanded in vitro. However, evidence from animal models of Treg...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28688236
DOI: 10.1016/j.trsl.2017.06.009

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