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Article

Domain-specific control of germ cell polarity and migration by multifunction Tre1 GPCR.

The Journal of cell biology - 4 Sept 2017

LeBlanc Michelle G, Lehmann Ruth

Abstract excerpt

The migration of primordial germ cells (PGCs) from their place of origin to the embryonic gonad is an essential reproductive feature in many animal species. In Drosophila melanogaster, a single G protein-coupled receptor, Trapped in endoderm 1 (Tre1), mediates germ cell polarization at the onset of active migration and directs subsequent migration of PGCs through the midgut primordium. How these different aspects...

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Identifiers

PMID: 28687666
DOI: 10.1083/jcb.201612053
PMCID: PMC5584160

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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