Article
Genetic risk factors for chemotherapy-induced nausea and vomiting in patients with cancer receiving cisplatin-based chemotherapy.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer - 1 May 2018
Yokoi Mari, Tsuji Daiki, Suzuki Kenichi, Kawasaki Yohei, Nakao Masahiko, Ayuhara Hideaki, Kogure Yuuki, Shibata Kazuhiko, Hayashi Toshinobu, Hirai Keita, Inoue Kazuyuki, Hama Toshihiro, Takeda Koji, Nishio Makoto, Itoh Kunihiko
Abstract excerpt
PURPOSE: Younger age and female sex have already been well-known risk factors for chemotherapy-induced nausea and vomiting (CINV), and 30-50% of cancer patients still suffer from CINV. Genetic polymorphisms are suggested to influence antiemetic treatment response. METHODS: This study included a subset of patients previously enrolled in a randomised controlled trial; 156 patients were evaluated. This study aimed...
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