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Article

MALT lymphoma: many roads lead to nuclear factor-κb activation

1 Jan 2011

Abstract excerpt

Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT) lymphoma is characterized genetically by several recurrent, but mutually exclusive, chromosome translocations. To date, it has been shown that at least the oncogenic products of t(1;14)(p22;q32)/BCL10-IGH, t(14;18)(q32;21)/IGH-MALT1 and t(11;18)(q21;q21)/API2-MALT1 activate the nuclear factor (NF)-κB activation pathway. Recently, A20,...

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PMID: 21261681
DOI: 10.1111/j.1365-2559.2010.03699.x

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