Article
High throughput sequencing reveals high specificity of TNFAIP3 mutations in ocular adnexal marginal zone B-cell lymphomas.
Hematological oncology - 1 Aug 2020
Vela Visar, Juskevicius Darius, Gerlach Magdalena M, Meyer Peter, Graber Anne, Cathomas Gieri, Dirnhofer Stefan, Tzankov Alexandar
Abstract excerpt
The majority of ocular adnexal (OA) lymphomas (OAL) are extranodal marginal zone lymphomas (MZL). First high throughput sequencing (HTS) studies on OA-MZL showed inconsistent results and the distribution of mutations in reactive lymphoid lesions of this anatomic region has not yet been sufficiently addressed. We characterized OAL and lymphoid lesions of the OA by targeted HTS. The study included 34 OA-MZL, 11...
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