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Article

Novel GPR34 and CCR6 mutation and distinct genetic profiles in MALT lymphomas of different sites.

Haematologica - 1 Aug 2018

Moody Sarah, Thompson Joe Sneath, Chuang Shih-Sung, Liu Hongxiang, Raderer Markus, Vassiliou George, Wlodarska Iwona, Wu Fangtian, Cogliatti Sergio, Robson Alistair, Ashton-Key Margaret, Bi Yingwen, Goodlad John, Du Ming-Qing

Abstract excerpt

Mucosa-associated lymphoid tissue (MALT) lymphoma originates from a background of diverse chronic inflammatory disorders at various anatomic sites. The genetics underlying its development, particularly in those associated with autoimmune disorders, is poorly characterized. By whole exome sequencing of 21 cases of MALT lymphomas of the salivary gland and thyroid, we have identified recurrent somatic mutations in 2...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Lymphoma, B-Cell, Marginal Zone

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Source

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Identifiers

PMID: 29674500
DOI: 10.3324/haematol.2018.191601
PMCID: PMC6068028

Genes

GPR34
CCR6
TET2
TNFAIP3
TNFRSF14
NOTCH1

Provenance

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