Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The emerging role of senescent cells in tissue homeostasis and pathophysiology

1 Jan 2015

Abstract excerpt

Cellular senescence is a state of permanent growth arrest and is thought to play a pivotal role in tumor suppression. Cellular senescence may play an important role in tumor suppression, wound healing, and protection against tissue fibrosis in physiological conditions in vivo. However, accumulating evidence that senescent cells may have harmful effects in vivo and may contribute to tissue remodeling, organismal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immune cells in cancer
Share to Neutrophil, Myeloperoxidase and Oxidative Mechanisms
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25994420
DOI: 10.3402/pba.v5.27743

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The emerging role of senescent cells in tissue homeostasis and pathophysiologyPMID 25994420Read ↗

Cellular Senescence: What, Why, and How.Semantic proximity Read ↗

Cellular Senescence: Aging, Cancer, and InjurySemantic proximity Read ↗

Insights from In Vivo Studies of Cellular SenescenceSemantic proximity Read ↗

Mechanisms of Cellular Senescence: Cell Cycle Arrest and Senescence Associated Secretory PhenotypeSemantic proximity Read ↗

Impact of Senescent Cell Subtypes on Tissue Dysfunction and Repair: Importance and Research QuestionsSemantic proximity Read ↗

Senescent cells at the crossroads of aging, disease, and tissue homeostasisSemantic proximity Read ↗

The role of p21 in cellular senescence and aging-related diseasesSemantic proximity Read ↗

Hallmarks of Cellular Senescence.Semantic proximity Read ↗

Cellular senescence: mechanisms and relevance to cancer and agingSemantic proximity Read ↗

The Jekyll and Hyde of Cellular Senescence in CancerSemantic proximity Read ↗

Understanding cellular senescence: pathways involved, therapeutics and longevity aidingSemantic proximity Read ↗

Cellular Senescence in the Lung: The Central Role of Senescent Epithelial CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.