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Advances and applications of genome-edited animal models for severe combined immunodeficiency

29 Oct 2024

Abstract excerpt

Severe combined immunodeficiency disease (SCID), characterized by profound immune system dysfunction, can lead to life-threatening infections and death. Animal models play a pivotal role in elucidating biological processes and advancing therapeutic strategies. Recent advances in gene-editing technologies, including zinc-finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs),...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 39846200
DOI: 10.24272/j.issn.2095-8137.2024.195

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