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Article

A CRISPR Path to Engineering New Genetic Mouse Models for Cardiovascular Research.

Arteriosclerosis, thrombosis, and vascular biology - 1 Jun 2016

Miano Joseph M, Zhu Qiuyu Martin, Lowenstein Charles J

Abstract excerpt

Previous efforts to target the mouse genome for the addition, subtraction, or substitution of biologically informative sequences required complex vector design and a series of arduous steps only a handful of laboratories could master. The facile and inexpensive clustered regularly interspaced short palindromic repeats (CRISPR) method has now superseded traditional means of genome modification such that virtually...

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Identifiers

PMID: 27102963
DOI: 10.1161/ATVBAHA.116.304790
PMCID: PMC4882230

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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