Article
The potential of shifting recombination hotspots to increase genetic gain in livestock breeding.
Genetics, selection, evolution : GSE - 4 Jul 2017
Gonen Serap, Battagin Mara, Johnston Susan E, Gorjanc Gregor, Hickey John M
Abstract excerpt
BACKGROUND: This study uses simulation to explore and quantify the potential effect of shifting recombination hotspots on genetic gain in livestock breeding programs. METHODS: We simulated three scenarios that differed in the locations of quantitative trait nucleotides (QTN) and recombination hotspots in the genome. In scenario 1, QTN were randomly distributed along the chromosomes and recombination was...
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